mecA XpressFISH®

The Blood Culture Tested Positive for S. aureus. Is it MRSA or MSSA?

Why you need to know the difference

Methicillin-resistant Staphylococcus aureus (MRSA) is one of the most common antimicrobial resistant pathogens in both the healthcare setting and in the community.1 Methicillin-resistance is almost exclusively caused by the presence and expression of the mecA gene that encodes a unique penicillin-binding protein (PBP2a) that has low affinity for methicillin and other beta-lactam drugs.2 It has been shown that MRSA infections can lead to increased hospital costs and extra length of stay.3,4

mecA XpressFISH is the FIRST and ONLY molecular assay that detects the active mecA gene from positive Staphylococcus aureus blood cultures

• Results 1-3 days earlier than conventional methods
• Allows for early and appropriate therapy for patients with MRSA and MSSA infections
• Enables de-escalation of vancomycin for patients with MSSA infections5

1. Dantes et al. JAMA Intern Med 2013; 173(21):1970-1978.
2. Gordon et al. Clin Infect Dis 2008; 46:S350-359.
3. Zimlichman et al. JAMA Intern Med 2013; 173(22):2039-2046.
4. Cosgrove et al. Infect Con Hosp Epide 2005; 26(2):166-174.
5. Bauer et al. Clin Infect Dis 2010; 51:1074-1080.